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Search Results for " thromboxane a2 "

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抑制剂 & 化合物

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Cat. No.	Product Name	Target	Signaling Pathways
T34862	Thromboxane A2 Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2
	Thromboxane A2, as an unstable intermediate between the prostaglandin endoperoxides and thromboxane B2, is a potent inducer of platelet aggregation and causes vasoconstriction.
T36548	Carbocyclic Thromboxane A2
	Carbocyclic Thromboxane A2 可用于生命科学领域的相关研究。其产品编号为 T36548，CAS号为 74034-56-3。
T36208	15(R)-Pinane Thromboxane A2 15(R)-Pinane Thromboxane A2
	15(R)-Pinane thromboxane A2 is the (R)-epimer of pinane thromboxane A2 . 15(R)-PTA2 does not inhibit collagen-induced platelet aggregation (IC50s = 120-130 μM). It does not affect gastric tone in isolated rat gastric fundus when used at concentrations of 0.5 or 1.5 μg/ml and is less effective than PTA2 at inhibiting prostaglandin-induced contraction of isolated rat stomach muscle.
T6236	Ozagrel 奥扎格雷,OKY-046,Domenan	Thrombin; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Ozagrel (Domenan) 是血栓烷 A2(TXA2) 合酶抑制剂，可抑制哮喘。它也是一种抗血小板剂，可选择性抑制人血小板聚集，IC50为 53.12 μM。
T6625	Ozagrel hydrochloride Ozagrel HCl,盐酸奥扎格雷,OKY-046 HCl	Thrombin; Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation; Proteases/Proteasome
	Ozagrel hydrochloride (OKY-046 HCl) 是一种选择性血栓素 A(2) 合成酶抑制剂，用于改善术后脑血管收缩和伴随的脑缺血。它是一种抗血小板剂，可选择性抑制人血小板聚集，IC50为 53.12 μM。
T11339	Furegrelate sodium U-63557A	PPAR	DNA Damage/DNA Repair; Metabolism
	Furegrelate sodium (U-63557A) 是口服有效的、血栓素合酶选择性抑制剂，抑制人血小板微粒体血栓素 A2 (TxA2) 合酶的 IC50为 15 nM。它正在开发作为抗血小板药物。
T17039	Terbogrel BIBV 308SE	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Terbogrel 是一种可口服的、具有选择性 thromboxane A2 受体拮抗剂（IC50 约为 10 nM），是一种 thromboxane A2 synthase 抑制剂（IC50 约为 10 nM）。Terbogrel 是一种抗血小板化合物，可抑制血小板聚集，是预防血栓的潜在化合物。
T12268	NTP42	Prostaglandin Receptor; PPAR	DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism
	NTP42 是血栓素 A2 (TXA2) 受体的拮抗剂，IC50为 3.278 nM，可用于肺动脉高压的相关研究。
T12771	RS-601	Leukotriene Receptor; Thrombin	GPCR/G Protein; Proteases/Proteasome
	RS-601 是一种有效的 leukotriene D4/thromboxane A2 双重抑制剂，对抗原诱导的气道高反应性（AHR）有抑制作用且在豚鼠哮喘模型中显示出平喘作用。
T11339L	Furegrelate	PPAR	DNA Damage/DNA Repair; Metabolism
	FUREGRELATE 是一种血栓素 A2 (TxA2) 合酶抑制剂，可减缓新生仔猪肺动脉高压的发展。
T31213	Dazmegrel UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485	PPAR	DNA Damage/DNA Repair; Metabolism
	Dazmegrel (UK 38,485) 是一种强效特异性血栓素 A2（TXA2）合成酶抑制剂，可用于预防正常妊娠中全血小板聚集增加。
T15577	Indobufen Ibustrin,吲哚布芬	COX	Immunology/Inflammation; Neuroscience
	Indobufen (Ibustrin) 是一种血小板聚集抑制剂，是下调单核细胞中的组织因子，可逆抑制血小板环氧合酶 (Cox) 的活性和血栓素 A2 (TxA2) 的合成。
T27630	Isbogrel CV4151,CV-4151,CV 4151	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Isbogrel (CV4151)是一种小分子血栓素A2合成酶(TXA2 synthase)抑制剂，可用来研究心律失常、短暂性脑缺血发作和血栓形成。
T15049	Daltroban BM-13505,SKF 96148	PPAR	DNA Damage/DNA Repair; Metabolism
	Daltroban (SKF 96148) (BM-13505) 是选择性和特异性的血栓素 A2 (TXA2) 受体拮抗剂。Daltroban 可以增加血管平滑肌细胞内钙。Daltroban 显示对再灌注损伤的保护作用。
T68022L	Sulotroban potassium BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base)	PPAR	DNA Damage/DNA Repair; Metabolism
	Sulotroban potassium 是一种小分子血栓素A2受体（TXA2R）拮抗剂，可用于研究心肌梗塞和血栓形成。
T11825	LCB-2853	PPAR	DNA Damage/DNA Repair; Metabolism
	LCB-2853 是一种有效的血栓素 A2/前列腺素 H2 （TXA2/PGH2）受体拮抗剂，具有抗血小板聚集、抗血管痉挛和抗血栓作用。
T0212	Seratrodast 塞曲司特,AA 2414,ABT-001	COX; Prostaglandin Receptor; PPAR	DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Seratrodast (ABT-001) 是一种血栓素 A2 受体 (TP) 拮抗剂，用于治疗哮喘。
T68086	Imitrodast	Thrombin	Proteases/Proteasome
	Imitrodast是一种小分子血栓素A2合成酶（TXA2 synthase）抑制剂，可用于治疗免疫系统疾病、呼吸系统疾病和心血管疾病，可用于研究动脉血栓形成、哮喘和冠状血管痉挛。
TQ0145	(R)-(+)-Bay-K-8644 (R)-(+)-Bay K 8644	Calcium Channel; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	(R)-(+)-Bay-K-8644 是一种 Ca2+ 通道激动剂，是二氢吡啶激动剂，抑制 Ba2+电流 (IBa)，诱导猫的中枢性呼吸抑制，通过竞争性拮抗血栓素 A2-前列腺素 H2 受体抑制血小板活化。
T0839	Ketoprofen 酮基布洛芬,RP-19583,酮洛芬	Apoptosis; COX; MRP	Apoptosis; Immunology/Inflammation; Neuroscience
	Ketoprofen (RP-19583) 是一种非甾体抗炎剂，能够有效地抑制COX 的活性，在人血单核细胞中，对 COX-1 和 COX-2 的IC50值分别为 2 nM 和 26 nM。
T1002	Etodolac Ultradol,AY-24236,依托度酸,Etodolic acid,Lodine	Retinoid Receptor; COX	Immunology/Inflammation; Metabolism; Neuroscience
	Etodolac (AY-24236) 是一种吡喃羧酸和非甾体抗炎药，具有解热和镇痛活性，对 COX 的 IC50为53.5 nM。
T23670	AH 22921 AH22921,AH-22921
	AH 22921 is an antagonist of thromboxane A2.
T22896	L-655,240	Others	Others
	thromboxane A2/prostaglandin endoperoxide receptor antagonist
T70871	Mipitroban
	Mipitroban is a thromboxane A2/prostaglandin H2 antagonist.
T70966	GR-36246
	GR-36246 is a Thromboxane A2-receptor blocker.
T70561	FCE-24265
	FCE-24265 is a calcium & thromboxane A2 synthase inhibitor.
T70737	HN 11500
	HN 11500 is an antithrombotic agent and thromboxane A2 receptor antagonist.
T68199	Nafagrel
	Nafagrel is a thromboxane A2 synthetase inhibitor.
T70541	IS-145
	IS-145 is a thromboxane A2 receptor antagonist.
T68287	Indobufen sodium
	Indobufen sodium is a Thromboxane A2 antagonist and Cyclooxygenase inhibitor.
T15252	Etersalate Etherylate,Eterylate	Others	Others
	Etersalate inhibits platelet function. It also reduces thromboxane A2 (TXA2) levels.
T28176	Nizofenone Y9179,Y-9179,Ekonal,Y 9179
	Nizofenone, a thromboxane A2 (TXA2) biosynthesis inhibitor, is used as a neuroprotective drug and used to treat stroke.
T71405	Domitroban
	Domitroban, also known as S-145, is a thromboxane (Tx) A2-receptor antagonist with partial agonistic activity in vascular smooth muscle.
T29722	AGN 191976
	AGN 191976 is a novel thromboxane A2-mimetic.
T22897	L-670,596	Others	Others
	thromboxane A2/prostaglandin endoperoxide receptor antagonist
TP2356	Triletide Triletida,Triletidum
	Triletide is a thromboxane A2 antagonist agent.
T68627	Ono 11119
	Ono 11119 is a thromboxane A2 antagonist.
T24310	L 657925 L-657925,L657925
	L 657925 is an antagonist of the thromboxane A2 receptor.
T28841	SQ 26655 SQ26655,SQ-26655
	SQ 26655 is an antagonist of thromboxane A2/prostaglandin H2.
T27575	ICI 192605 ICI192605,ICI-192605
	ICI 192605 is a potent thromboxane A2 receptor (TP receptor) antagonist.
T70739	KW 4099
	KW 4099 is a thromboxane A2 antagonist.
T71233	HN-11501
	HN-11501 is a Thromboxane A2 receptor antagonist.
T68198	Nafagrel hydrochloride
	Nafagrel hydrochloride is a thromboxane A2 synthetase inhibitor.
T71178	Nafagrel hydrochloride hemihydrate
	Nafagrel hydrochloride hemihydrate is a thromboxane A2 synthetase inhibitor.
T70709	FCE-27262
	FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist.
T6236L	Ozagrel Sodium KCT 0809,KCT-0809,Xanbo,KCT0809,Cataclot,奥扎格雷钠
	Ozagrel Sodium is a thromboxane A2 synthase inhibitor. It is used to treat cerebrovascular diseases.
T28242	Ono 3708 Ono-3708,Ono3708
	Ono-3708 is a potent antagonist of the thromboxane A2/prostaglandin endoperoxide receptor in vitro and in vivo.
T70694	HA-29
	HA-29 is an inhibitor of thromboxane A2 and prostaglandin endoperoxide receptors.
T29200	Z-335 sodium Z 335,Z335,Z-335
	Z-335 Salt, a thromboxane A2 receptor antagonist, is used potentially for the treatment of arterial occlusive disease.
T17189	U-46619 9,11-Methanoepoxy PGH2	Progesterone Receptor; PPAR	DNA Damage/DNA Repair; Metabolism; Others
	U-46619是一种有效的TXA2激动剂，是一种血栓素A2类似物（内过氧化物），有诱导肌球蛋白轻链9 (Myl9)基因缺失小鼠主动脉平滑肌(SM)收缩的功能。

化合物

Thromboxane A2

Cat.No: T34862

Synonym: Rabbit aorta contracting substance,TXA-2,TXA2,TXA 2

Carbocyclic Thromboxane A2

Cat.No: T36548

15(R)-Pinane Thromboxane A2

Cat.No: T36208

Synonym: 15(R)-Pinane Thromboxane A2

Cat.No: T6236

Synonym: 奥扎格雷,OKY-046,Domenan

Target: Thrombin, Prostaglandin Receptor

Ozagrel hydrochloride

Cat.No: T6625

Synonym: Ozagrel HCl,盐酸奥扎格雷,OKY-046 HCl

Target: Thrombin, Prostaglandin Receptor

Furegrelate sodium

Cat.No: T11339

Synonym: U-63557A

Target: PPAR

Cat.No: T17039

Synonym: BIBV 308SE

Target: Prostaglandin Receptor

Cat.No: T12268

Target: Prostaglandin Receptor, PPAR

Cat.No: T12771

Target: Leukotriene Receptor, Thrombin

Cat.No: T11339L

Target: PPAR

Cat.No: T31213

Synonym: UK-38,485,UK 38485,UK 38,485,UK38,485,UK-38485

Target: PPAR

Cat.No: T15577

Synonym: Ibustrin,吲哚布芬

Target: COX

Cat.No: T27630

Synonym: CV4151,CV-4151,CV 4151

Target: Prostaglandin Receptor

Cat.No: T15049

Synonym: BM-13505,SKF 96148

Target: PPAR

Sulotroban potassium

Cat.No: T68022L

Synonym: BM 13177 potassium,Sulotroban potassium(72131-33-0 Free base)

Target: PPAR

Cat.No: T11825

Target: PPAR

Cat.No: T0212

Synonym: 塞曲司特,AA 2414,ABT-001

Target: COX, Prostaglandin Receptor, PPAR

Cat.No: T68086

Target: Thrombin

(R)-(+)-Bay-K-8644

Cat.No: TQ0145

Synonym: (R)-(+)-Bay K 8644

Target: Calcium Channel, PPAR

Cat.No: T0839

Synonym: 酮基布洛芬,RP-19583,酮洛芬

Target: Apoptosis, COX, MRP

Cat.No: T1002

Synonym: Ultradol,AY-24236,依托度酸,Etodolic acid,Lodine

Target: Retinoid Receptor, COX

Cat.No: T23670

Synonym: AH22921,AH-22921

Cat.No: T22896

Target: Others

Cat.No: T70871

Cat.No: T70966

Cat.No: T70561

Cat.No: T70737

Cat.No: T68199

Cat.No: T70541

Indobufen sodium

Cat.No: T68287

Cat.No: T15252

Synonym: Etherylate,Eterylate

Target: Others

Cat.No: T28176

Synonym: Y9179,Y-9179,Ekonal,Y 9179

Cat.No: T71405

Cat.No: T29722

Cat.No: T22897

Target: Others

Cat.No: TP2356

Synonym: Triletida,Triletidum

Cat.No: T68627

Cat.No: T24310

Synonym: L-657925,L657925

Cat.No: T28841

Synonym: SQ26655,SQ-26655

Cat.No: T27575

Synonym: ICI192605,ICI-192605

Cat.No: T70739

Cat.No: T71233

Nafagrel hydrochloride

Cat.No: T68198

Nafagrel hydrochloride hemihydrate

Cat.No: T71178

Cat.No: T70709

Cat.No: T6236L

Synonym: KCT 0809,KCT-0809,Xanbo,KCT0809,Cataclot,奥扎格雷钠

Cat.No: T28242

Synonym: Ono-3708,Ono3708

Cat.No: T70694

Cat.No: T29200

Synonym: Z 335,Z335,Z-335

Cat.No: T17189

Synonym: 9,11-Methanoepoxy PGH2

Target: Progesterone Receptor, PPAR

Cat. No.	Product Name	Target	Signaling Pathways
T36831	9-Oxononanoic Acid 9-ONA	Phospholipase; CPT	Metabolism
	9-Oxononanoic Acid是一种氧化脂肪酸，由亚油酸自氧化形成，它能提高磷脂酶 A2（PLA2）的活性，并增加离体人体血浆中血栓素 B2 的生成。9-Oxononanoic Acid 能减少肝脏新脂肪酸的合成，并提高大鼠肝脏肉碱棕榈酰转移酶（β-氧化的标志物）的活性。

天然产物

9-Oxononanoic Acid

Cat.No: T36831

Synonym: 9-ONA

Target: Phospholipase, CPT

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